药物化学系

唐培 教授(博士生导师)

来源: 发布时间:2024年07月13日 点击数:

唐培教授(博士生导师)

单位:金沙威尼斯欢乐娱人城 药物化学系

通讯地址:成都市人民南路三段17号 金沙威尼斯欢乐娱人城 610041

E-mail:peitang@scu.edu.cn


教育与工作经历:

2001.09-2005.06 金沙威尼斯欢乐娱人城 理学学士

2005.09-2008.06 金沙威尼斯欢乐娱人城理学硕士(导师:王锋鹏教授)

2008.09-2011.12 金沙威尼斯欢乐娱人城理学博士(导师:王锋鹏教授)

2012.05-2014.09 重庆大学药学院 博士后研究(导师:秦勇教授)

2014.09-2016.08 重庆大学药学院 讲师

2016.09-2018.06 重庆大学药学院 副教授

2018.07-2019.08 金沙威尼斯欢乐娱人城 特聘副研究员

2019.09-2023.08 金沙威尼斯欢乐娱人城 副教授

2023.09-至今 金沙威尼斯欢乐娱人城 教授


研究方向:

1. 药物绿色合成新工艺

2. 手性药物的不对称合成

3. 具有重要生理活性的天然药物发现和全合成


主持与参与的科研项目:

1.国家自然科学基金面上项目,2024-2027,负责人

2.国家自然科学基金区域重点项目,2021-2025,参与(排名第二)

3.四川省应用基础研究专项,2021-2023,负责人

4.厅市共建中枢神经系统药物四川省重点实验室开放课题,2021-2023,负责人

5.金沙威尼斯欢乐娱人城-泸州市人民政府战略合作项目,2022-2024,负责人

6.金沙威尼斯欢乐娱人城引进人才启动费,2018-2021,负责人

7.国家自然科学基金青年科学基金,2016-2018,负责人

8.中国博士后科学基金面上项目,2012-2014,负责人

9.重庆市基础科学与前沿技术研究专项,2016-2019,负责人


曾获奖项:

2015年 教育部高等学校科学研究优秀成果奖自然科学一等奖(9/15)

2019年 金沙威尼斯欢乐娱人城本科优秀教学三等奖

2020年 金沙威尼斯欢乐娱人城本科优秀教学三等奖

2021年 金沙威尼斯欢乐娱人城本科优秀教学一等奖

2021年 金沙威尼斯欢乐娱人城课堂教学质量优秀奖

2021年 金沙威尼斯欢乐娱人城第四届“探究式-小班化”教学竞赛三等奖

2022年 金沙威尼斯欢乐娱人城红叶实验奖教金优秀实验课程组

2023年 挑战杯大学生课外学术科技作品竞赛校级二等奖

2023年 挑战杯大学生课外学术科技作品竞赛校级三等奖

2023年 金沙威尼斯欢乐娱人城优秀共产党员


学术任职:

2021年入选四川省高层次人才引进计划(天府峨眉计划)

2019.07-至今 《Chinese Chemical Letters》(中国化学快报)青年编委

2020.08-至今 《Green Synthesis and Catalysis》(绿色合成与催化)青年编委

2023.01-至今 《Frontiers of Chemical Science and Engineering》(化学科学与工程前沿)编委

2019.08-至今 《Pharmaceutical Fronts》(制药前沿)编委

2021.04-至今 四川省药学会药物化学专委会委员


近期代表性论文:

1.Xiangtao Chen, Huijing Wang,Jie Zeng, Qiuhong Li, Tonghui Zhang, Qiaoyun Yang,Pei Tang*,Fen-Er Chen*. Stereodivergent Total Synthesis of Tacaman Alkaloids.Angew. Chem. Int. Ed.2024,63,e202407149.

2.Guo-Tai Zhang, Gen Li, Linxi Wan, Xinxin Pu, Junhai Chang,Pei Tang*,Fen-Er Chen*. Asymmetric Total Synthesis of Anti-HBV Drug Entecavir: CatalyticStrategies for the Stereospecific Construction of DenselySubstituted Cyclopentene Cores.Org. Lett.2024,26, 4818.

3.Zhi Yang, Shangxian Luan, Linxi Wan, Jingxi Chen, Xiaofang Wei,Pei Tang*,Fen-Er Chen*. Iridium-catalyzed asymmetric hydrogenation of5-hydroxypicolinate pyridinium salts under batchand flow: stereodefined access to cis-configuratedhydroxypiperidine esters.Org. Chem. Front.2024,11, 3225.

4.Zhi Yang, Hanlin Chen, Linxi Wan, Xinyi Feng, Lingshuang Ma,Pei Tang*,Fen-Er Chen*. Sustainable synthesis of long-acting localanesthetics ropivacaine and levobupivacaine underbatch and continuous flow via asymmetrichydrogenation.Org. Chem. Front.2024,11, 2891.

5.Zhi Yang, Yu Chen, Linxi Wan, Yuxiao Li, Dan Chen, Jianlin Tao,Pei Tang*,Fen-Er Chen*. Iridium-catalyzed asymmetric, complete hydrogenation of pyrimidinium salts under batch and flow.Green Chem.2024,26, 317.

6.Bo Yin, Xiaohuan Li, Zi-Xiang Li, Xiao-Xin Zhu, Lan Zhang, Xian-Li Zhou, Jin-Bu Xu,Feng-Zheng Chen,Pei Tang*, Feng Gao*. Adenophorone, An Unprecedented Sesquiterpene from Eupatorium adenophorum: Structural Elucidation, Bioinspired Total Synthesis and Neuroprotective Activity Evaluation.Angew. Chem. Int. Ed.2023,62, e202306326.

7.Weijian Li, Shiqi Huang, Meifen Jiang, Yu Chen, Zhi Yang,Pei Tang*, Fener Chen*. An Efficient and Eco-Friendly Synthesis of Protoberberineand 13-Me Protoberberine Alkaloids via Electrochemical Acceptorless Dehydrogenation.ChemCatChem2023,15, e202201553.

8.Lili Song, Zhigang Liu, Minjie Liu,Pei Tang*, Fener Chen*. Efficient and Scalable Synthesis of Ketoprofen: A Pyrolytic Aromatization Approach.Org. Process Res. Dev.2023,27, 922.

9.Wen Zhang, Zhenzhen Wang, Guodan Lin, Yansong Xue, Mengjuan Wu,Pei Tang*, Fener Chen*. Stereoselective Total Syntheses of C18-Oxo Eburnamine-Vincamine Alkaloids.Org. Lett.2022,24, 2409.

10.Yi An, Mengjuan Wu, Weijian Li, Yaling Li, Zhenzhen Wang, Yansong Xue,Pei Tang*, Fener Chen*.The Total Synthesis of (−)-Strempeliopine via Palladium-catalyzed Decarboxylative Asymmetric Allylic Alkylation.Chem. Commun.2022,58, 1402.

11.Xiaofen Yi, Xueyu Long, Yu Chen, Xiangling Cen,Pei Tang*, Fener Chen*.Asymmetric Total Synthesis of Prostaglandin C2 TBS Ether.Chem. Commun.2022,58, 6000.

12.Zhi Yang, Yu Chen, Linxi Wan, Xiangling Cen,Pei Tang*, Fener Chen*. Catalytic Asymmetric Total Synthesis of Diazabicyclooctane β-Lactamase Inhibitors Avibactam and Relebactam.Chem. Commun.2022,58, 10869.

13.Wenchang Chen, Xiaofen Yi, Hongmin Qu, Yu Chen,Pei Tang*, Fener Chen*. Concise Syntheses of 13-Methylprotoberberine and 13-Methyltetrahydroprotoberberine Alkaloids.Chin. Chem. Lett.2022,33, 5080.

14.Wen Zhang, Yansong Xue, Srihari Konduri, Guodan Lin, Mengjuan Wu,Pei Tang*, Fener Chen*. Unified Total Synthesis of Eburnamine-Vincamine Indole Alkaloids Based on Catalytic Asymmetric Hydrogenation/Lactamization Cascade.Green Synth. Catal.2022,3, 291.

15.Xiangtao Chen, Lei Yu, Huijing Wang, Wen Zhang,Pei Tang*, Fener Chen*.Stereoselective Total Synthesis of (±)-Vindeburnol and (±)-16-Epi-vindeburnol.Chem. Commun.2021,57, 11669.

16.Weijian Li, Meifen Jiang, Wenchang Chen, Yu Chen, Zhi Yang,Pei Tang*, Fener Chen*. Total Synthesis of (−)-Canadine, (−)-Rotundine, (−)-Sinactine, and (−)-Xylopinine Using a Last-Step Enantioselective Ir-Catalyzed Hydrogenation.J. Org. Chem.2021,86, 8143.

17.Wen Zhang, Xiangtao Chen, Yi An, Jiaqi Wang, Chunlin Zhuang,Pei Tang*, Fener Chen*. Enantioselective Total Syntheses of (–)-20-epi-Vincamine and (–)-20-epi-Eburnamonine by Ir-Catalyzed Asymmetric Imine Hydrogenation/Lactamization Cascade.Chem. Eur. J.2020,26, 10439.

18.Dan Jiang (co-first author),Pei Tang(co-first author), Qiuyuan Tan, Zhao Yang, Ling He*, Min Zhang*. Enantioselective Alkynylation of Isatins: A Combination of Metal Catalysis and Organocatalysis.Chem. Eur. J.2020,26, 15830.

19.Huijing Wang, Qiuyan Dong, Qinxia Xie,Pei Tang*. Asymmetric Synthesis of ABC Tricyclic Systems in Daphniphyllum Alkaloid.Chin. Chem. Lett.2020,31, 685.

20.Qinxia Xie, Hai-Jiao Long, Qiong-Yin Zhang,Pei Tang*, Jun Deng*. Enantioselective Syntheses of 4H‑3,1-Benzoxazines via Catalytic Asymmetric Chlorocyclization of o-Vinylanilides.J. Org. Chem.2020,85, 1882.

21.Pei Tang, Huijing Wang, Wen Zhang, Fener Chen*. Asymmetric Catalytic Hydrogenation of Imines and Enamines in Natural Product Synthesis.Green Synth. Catal.2020,1, 26.

22.Pei Tang, Biao Nie, Jiuzhong Huang, Yingjun Zhang, Ji Zhang, Fener Chen*. Recent Advances of Pharmaceutical Process Chemistry and Its Innovation in China Part 1.Pharma. Fronts2020,2, e28.


编辑:金沙威尼斯欢乐娱人城

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