龚涛 教授（博士生导师）
单位：金沙威尼斯欢乐娱人城，药剂学系
通讯地址：成都市人民南路三段17号金沙威尼斯欢乐娱人城
电话/传真：（028）85501615
E-mail:gongtaoy@126.com
简历
教育经历:
2001/09 - 2004/07: 金沙威尼斯欢乐娱人城，药剂学博士学位/博士学历，
1992/09 - 1995/07:华西医科大学，药剂学硕士学位/硕士学历，
1987/09 - 1992/07:华西医科大学，药学本科
工作经历:
2011/07– 现今: 金沙威尼斯欢乐娱人城药剂学系，教授
2004/07–2011/06: 金沙威尼斯欢乐娱人城药剂学系，讲师、副教授
1995/07–2001/07: 华西医科大学制药厂，开发部副主任
主要社会职务
国家药监局新药评审专家
四川省药监局新药评审专家
中国药学会药剂专委会委员
四川省药学会药剂专委会委员
人才称号
四川省有突出贡献的优秀专家
四川省卫健委学术和技术带头人
金沙威尼斯欢乐娱人城青年骨干教师
曾获奖项
2021年国家科技进步奖二等奖（第二完成人）
2021年金沙威尼斯欢乐娱人城第七届“姜维平优秀教学奖”二等奖
2018年四川省第八届高等教育优秀教学成果三等奖（第六完成人）
2018年度九三学社成都市委优秀社员
2015年度四川省科技进步一等奖（第三完成人）
2011年度四川省科技进步一等奖（第五完成人）
研究方向
缓控释和微粒给药系统的关键技术及应用研究
药物制剂新技术及其应用研究
主持科研项目
课题负责人：
国家自然科学基金面上项目：82173758；2022年1月至2025年12月
国家自然科学基金面上项目：81872804；2019年1月至2022年12月
国家自然科学基金面上项目：81673359；2017年1月至2020年12月
国家自然科学基金面上项目：81273443；2013年1月至2016年12月
国家自然科学基金面上项目：30873165；2009年1月至2011年12月
四川省科技支撑项目：2008SZ0022；2008年1月至2010年12月
子课题负责人：
科技部重大新药创制关键技术：2011ZX09501-001-01；2010年5月至2013年5月
科技部重大新药创制：2014ZX09507001002；2014年1月至2016年12月
脑部肿瘤系统靶向性纳米药物的工程化制备关键技术研究：2013CB932504-2；2013年1月至2017年12月
四川省科技支撑计划：2016KJT0017-2015SZ0019；2015年1月至2017年12月
四川省重大科技专项项目：2018SZDZX0018-2；2018年7月至2021年9月
授权专利：
一种高尔基体靶向的粘多糖纳米胶束及其制备方法与应用：ZL 201811521626.1
一种白蛋白结合型吲哚菁绿抗肿瘤光热制剂及其制备方法：ZL 201811297855.X
一种载药网状原位相变凝胶缓释系统及其制备方法：ZL 201811171012.5
一种靶向至肝星状细胞的透明质酸纳米胶束及其制备方法和应用：ZL201710917937.9
一种小分子药物原位相变凝胶缓释系统及其制备方法：201710480564.3/201810909188.X/201810910942.1
一种载含酚羟基难溶性药物的脂质体及制备方法和应用：ZL 201710155343.9
TYPE POLYPEPTIDE TARGETING TUMORS,美国发明专利授权号：US10428114
一种达比加群酯纳米混合胶束及其制备方法：ZL 201610441009.5
一种鬼臼毒素类药物的靶向给药制剂：ZL 201410770026.4
一种长循环的氧化石蒜碱有机酸复合物新制剂：201610827478.0
一种透明质酸-阳离子药物离子对微粒：ZL 201510555003.6
一种9-硝基喜树碱混合胶束冻干粉针及其制备方法：ZL 201210035050.4
一种提高桑色素口服生物利用度的药物组合物：ZL201110275082.7
一种提高生物利用度的氧化石蒜碱组合物及其制剂：ZL201210252981.X
一种α-细辛脑混合胶束注射剂及其制备方法、应用及其冻干粉针制剂：ZL 200910059924.8
一种细辛脑注射剂及其制备方法：ZL 200910164296.X
丹参酚酸B磷脂复合物及其制备方法：ZL 200710051038.1
喜树碱衍生物磷脂复合物脂质纳米粒制剂及其制备方法：ZL 200710048481.3
近十年发表论文：
2021年
1. Caifeng Deng, Quan Zhang, Penghui He, Bin Zhou, Ke He, Xun Sun, Guanghua Lei*,Tao Gong*& Zhirong ZhangTargeted apoptosis ofmacrophages and osteoclasts in arthritic joints is effective against advanced inflammatory arthritis Nature Communication, (2021) 12:2174
2. Tan, Tiantian; Yang, Qin*; Chen, Dan ; Zhao, Juan; Xiang, Ling; Feng, Jiaxing;
Song,Xu;Gong, Tao* Chondroitin sulfate-mediated albumin corona nanoparticles for the
treatment of breast cancer Asian Journal of Pharmaceutical Sciences,16 (2021) 508–518
3. Hongli Zhou, Dan Chen, Ting Gong, Qin He, Chenqi Guo, Pei Zhang, Xu Song, Jinghua Ruan*,Tao Gong*Chlorogenic acid sustained-release gel for treatment of glioma and hepatocellular carcinoma European Journal of Pharmaceutics and Biopharmaceutics，166 (2021) 103–110
4.Ting Zhaoa, Hongli Zhoua, Wanyan Wua, Xu Songa，bandTao Gong*aA multistage oral delivery system of PTX for improving oral bioavailability and enhancing anticancer efficacy Drug Development and Industrial Pharmacy 2021,47(2):259-267
2020年
1. Ting Zhao, Hongli Zhou, Lei Lei, Chenqi Guo, Qin Yang, Ting Gong, Xun Sun, Xu Song* ,Tao Gong*, Zhirong Zhang a A new tandem peptide modified liposomal doxorubicin for tumor “ecological therapy” Nanoscale, 2020,12, 3359 – 3369
2. Wenhao Li, Chuchu Zhou, Yao Fu, Tijia Chen, Xing Liu, Zhirong Zhang,Tao Gong*Targeted delivery of hyaluronic acid nanomicelles to hepatic stellate cells in hepatic fibrosis rats Acta Pharmaceutica Sinica B 2020; 10(4):693—710
3. Shi Luo†, Jiaxing Feng†, Linyu Xiao†, Ling Guo‡, Lang Deng†, Zhengwu Du†, Yuan Xue†, Xu Song†, Xun Sun†, Zhi-Rong Zhang†, Yao Fu†,Tao Gong*† Targeting self-assembly peptide for inhibiting breast tumor progression and metastasis Biomaterials 249 (2020) 120055(online)
4. Ting Gong, Tiantian Tan, Pei Zhang, Haohuan Li, Caifeng Deng, Yuan Huang,Tao Gong *, Zhirong Zhang Palmitic acid-modified bovine serum albumin nanoparticles target scavenger receptor-A on activated macrophages to treat rheumatoid arthritis Biomaterials 258 (2020) 120296
5.Jingwen Luo,Tao Gong*and Lixin Ma,* Chondroitin-Modified Lipid Nanoparticles Target the Golgi to Degrade Extracellular Matrix for Liver Cancer Management Carbohydrate Polymer 249(2020)116887
6. Pei Zhang, Dan Chen, Yanxin Tian, Haohuan Li, Ting Gong, Jingwen Luo, Jinghua Ruan,Tao Gong*, Zhirong Zhang Comparison of three in-situ gels composed of different oil types International Journal of Pharmaceutics 587 (2020) 119707
2019年
1. Jingwen Luo, Pei Zhang, Rong Liu, Xinchao Li, Peng Hua, Shujie Li, Tianyi Zhang, Ting Zhang, Yao Fu, Xu Song*,Tao Gong*, Zhirong Zhang Efcient weapon for protracted warfare to malaria: A chondroitin sulfate derivates-containing injectable, ultra-long-lasting meshy-gel system Carbohydrate Polymers 214 (2019) 131–141
2. Jingwen Luo, Pei Zhang, Ting Zhao, Mengdi Jia, Peng Yin, Wenhao Li, Zhi-Rong Zhang, Yao Fu, andTao Gong*Golgi Apparatus-Targeted Chondroitin Modified Nanomicelles Suppress Hepatic Stellate Cell Activation for the Management of Liver Fibrosis : ACS Nano 2019, 13, 4, 3910−3923
3. Ting Gong, Xu Song*, Liuqing Yang, Tijia Chen, Ting Zhao, Tao Zheng, Xun Sun,Tao Gong*, Zhirong Zhang Spontaneously formed porous structure and M1 polarization effect of Fe3O4nanoparticles for enhanced antitumor therapy International Journal of Pharmaceutics 559 (2019) 329–340
4. Ting Zhanga,b, Xianyan Qina, Xi Caoa, Wenhao Lia, Tao Gonga*, Zhirong Zhanga
Thymopentin-loaded phospholipid-based phase separation gel with long-lasting immunomodulatory
effects: in vitroand in vivo studies Acta Pharmacologica Sinica 40,514–521(2019)
5. Haohuan Li, Pei Zhang, Jingwen Luo, Danrong Hu, Yuan Huang, Zhi-Rong Zhang, Yao Fu andTao Gong* Chondroitin Sulfate-Linked Prodrug Nanoparticles Target the Golgi Apparatus for Cancer Metastasis Treatment ACS Nano 2019, 13, 8,9386-9396
6. Qin Yang, Tiantian Tan, Juan Zhao, Chuchu Zhou, Chenqi Guo, Zhuoya Wan, Xu Song* andTao Gong* A reversible decomposition approach for the formation of injectable, excipient-free, self-assembling nanocrystals chemical communication 2019, 55, 3144—3147
7. Caifeng Deng, Quan Zhang, Mengdi Jia, Jin Zhao, Xun Sun,Tao Gong*and Zhirong Zhang Tumors and Their Microenvironment Dual-Targeting Chemotherapy with Local Immune Adjuvant Therapy for Effective Antitumor Immunity against Breast Cancer Advanced Science 2019, 6, 1801868
8. Chuchu Zhou, Xu Song*, Chenqi Guo, Yulu Tan, Juan Zhao, Qin Yang,Dan Chen, Tiantian Tan, Xun Sun,Tao Gong*, and Zhi-Rong Zhang An alternative and injectable preformed albumin-bound anticancer drug delivery system for anticancer and antimetastasis treatmentACS Appl. Mater. Interfaces, ACS Appl Mater Interfaces. 13;11(45):42534-42548
9. Ting Gong, Pei Zhang, Caifeng Deng, Yu Xiao,Tao Gong*& Zhirong Zhang An effective and safe treatment strategy for rheumatoid arthritis based on human serum albumin and Kolliphor® HS 15 Nanomedicine (Lond). (2019)14(16):2169-2187
10.Ting Zhanga,b, Jingwen Luob, Qiang Pengc, Jianxia Donga,b, Yunuo Wangb,Tao Gong*b,Zhirong ZhangbInjectable and biodegradable phospholipid-based phase separation gel for sustained delivery of insulin Colloids and Surfaces B: Biointerfaces 176 (2019) 194–201
2018年
1.Tijia Chen, Ting Gong, Ting Zhao, Yao Fu, Zhirong Zhang,Tao Gong*A comparison study between lycobetaine-loaded nanoemulsion and liposome using nRGD as therapeutic adjuvant for lung cancer therapy European Journal of Pharmaceutical Sciences 111(2018)293-302
2. Mengdi Jia, Caifeng Deng, Jingwen Luo, Pei Zhang, Xun Sun, Zhirong Zhang,Tao Gong*. A novel dexamethasone-loaded liposome alleviates rheumatoid arthritis in rats. International Journal of Pharmaceutics, 2018, 540: 57-64.
3. Xing Liua,b, Wenhao Lia, Tijia Chena, Qin Yanga, Ting Huangb, Yao Fua,Tao Gonga,*, Zhirong ZhangaHyaluronic acid-modified micelles encapsulating Gem-C12and HNK for glioblastoma multiforme chemotherapy Molecular Pharmaceutics 2018, 15, 1203−1214
4. L.Q. Yang, X. Song, T. Gong, K.J. Jiang, Y.Y. Hou, T.J. Chen, X. Sun, Z.R. Zhang,Tao Gong*, Development a hyaluronic acid ion-pairing liposomal nanoparticle for enhancing anti-glioma efficacy by modulating glioma microenvironment, Drug Deliv, 25 (2018) 388-397.
5. Liuqing Yang, Xu Song, Ting Gong, Luyao Wang, Ting Zhao, Lin Li, Chuchu Zhou, Xun Sun, Zhirong Zhang,Tao Gong*Enhanced anti-tumor and anti-metastasis efficacy against breast cancer with an intratumoral injectable phospholipids-based phase separation gel co-loaded with 5-fluotouracil and magnesium oxide by neutralizing acidic microenvironment International Journal of Pharmaceutics 2018, 547(1–2)：181-189
2017年
1. Caifeng Deng, Quan Zhang,*,Yao Fu, Xun Sun,Tao Gong*, and Zhirong Zhang Coadministration of Oligomeric Hyaluronic Acid-Modified Liposomes with Tumor-Penetrating Peptide-iRGD Enhances the Antitumor Efficacy of Doxorubicin against Melanoma ACS Appl. Mater. Interfaces 2017, 9, 1280−1292
2. Ting Zhang, Jingwen Luo, Yao Fu, Hanmei Li, Rui Ding∗,Tao Gong∗,Zhirong Zhang Novel oral administrated paclitaxel micelles with enhanced bioavailability and antitumor efficacy for resistant breast cancer Colloids and Surfaces B: Biointerfaces 150（2017）89-97
3. Caifeng Deng, Mengdi Jia, Guangfei Wei, Tiantian Tan, Yao Fu, Huile Gao, Xun Sun, Quan Zhang*Tao Gong*and Zhirong Zhang Inducing Optimal Antitumor Immune Response through Coadministering iRGD with Pirarubicin Loaded Nanostructured Lipid Carriers for Breast Cancer Therapy Molecular Pharmaceutics 2017, 14, 296−309
4. Tijia Chen, Ting Gong, Ting Zhao, Xing Liu, Yao Fu, Zhirong Zhang,Tao Gong*Paclitaxel loaded phospholipid-based gel as a drug delivery system for local treatment of glioma International Journal of Pharmaceutics 528 (2017) 127–132
5. Tijia Chen, Xu Song, Ting Gong, Yao Fu, Liuqing Yang, Zhirong Zhang,Tao Gong∗nRGD modified lycobetaine and octreotide combination delivery system to overcome multiple barriers and enhance anti-glioma efficacy Colloids and Surfaces B: Biointerfaces 156 (2017) 330–339
2016年
1.Jianxia Dong,Xu Song,Xianghong Lian, Yao Fu,Tao Gong*Subcutaneously injected ivermectin-loaded mixed micelles: formulation, pharmacokinetics, and local irritation study Drug Delivery, 2016; 23(7): 2220–2227
2.Yu Zhang,Ying Zhong,Mei Hu,Nanxi Xiang,Yao Fu,Tao Gong*&Zhirong ZhangIn vitro and in vivo sustained release of exenatide from vesicular phospholipid gels for type II diabetes Drug Development and Industrial Pharmacy
2016, 42(7): 1042-1049
3. Wenhao Li, Xiaoli Yi, Xing Liu, Zhirong Zhang, Yao Fu*,Tao Gong*Hyaluronic acid ion-pairing nanoparticles for targeted tumor therapy Journal of Controlled Release 225 (2016) 170–182
4. Jing-Wen Luo, Ting Zhang, Quan Zhang, Xi Cao, Xin Zeng, Yao Fu, Zhi-Rong Zhang,Tao Gong∗A novel injectable phospholipid gel co-loaded with doxorubicin and bromotetrandrine for resistant breast cancer treatment by
intratumoral injectionColloids and Surfaces B: Biointerfaces 140 (2016) 538–547
5. Nanxi Xiang, Xu Zhou, Xinyi He, Yu Zhang, Jinjie Zhang, Zhi-Rong Zhang, Xun Sun,Tao Gong*, Yao Fu* An Injectable Gel Platform for the Prolonged Therapeutic Effect of Pitavastatin in the Management of Hyperlipidemia Journal of Pharmaceutical Sciences 105 (2016) 1148—1155
6. Jing-Wen Luo, Zhi-Rong Zhang,Tao Gong*and Yao Fu* one-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine International Journal of Nanomedicine 2016:11 1051–1065
7. Mengxin Wang, Fengyin San, Yang Zou, Xun Sun, Zhi-Rong Zhang, Yao Fu*,Tao Gong* Pharmacokinetic and pharmacodynamic study of phospholipid-based phase separation gels for once a month administration of octreotide Journal of Controlled Release 2016，230：45-56
8. Xu Song, ZhuoyaWan, TijiaChen, Yao Fu, Kejun Jiang, Xiaoli Yi, Huan Ke, Jianxia Dong, Liuqing Yang, Lin Li, Xun Sun,Tao Gong*, Zhirong Zhang*
Development of a Multi-Target Peptide for Potentiating Chemotherapy by Modulating Tumor Microenvironment Biomaterials 108 (2016) 44-56
9. Quan Zhang†, Caifeng Deng†, Yao Fu, Xun Sun,Tao Gong*, Zhirong Zhang Repeated administration of hyaluronic acid coated liposomes with improved pharmacokinetics and reduced immune response Molecular Pharmaceutics 2016，13（6）1800-1808
2015年
1．Huan Liu, Hua Lu, Longfei Liao, Xuanmiao Zhang,Tao Gong*, and Zhirong Zhang Lipid nanoparticles loaded with 7-ethyl-10-hydroxycamptothecin phospholipid complex: in vitro and in vivo studies Drug Deliv, 2015，22(6):701-709
2.XuSong，Qing Lin，Ling Guo，Yao Fu，Jianfeng Han，Huan Ke，Xun Sun，Tao Gong*，Zhirong Zhang* Rifampicin Loaded Mannosylated Cationic Nanostructured Lipid Carriers for Alveolar Macrophage-specific Delivery
Pharm Res 2015，32(5):1741--1751
3. Xiaoli Yi, Xianghong Lian, Jianxia Dong,Zhuoya Wan, Chunyu Xia, Xu Song, Yao Fu*Tao Gong*Zhirong ZhangCo-delivery of pirarubicin and paclitaxel by human serum albumin nanoparticles to enhance antitumor effect and reduce systemic toxicity in breast cancersMolecular Pharmaceutics
2015, 12 (11), 4085–4098
4.Ting Zhang1, Qiang Peng1, Feng-Ying San, Jing-Wen Luo, Meng-Xin Wang, Wen-Qi Wu,Tao Gong*, Zhi-Rong Zhang**A high-efficiency, low-toxicity, phospholipids-based phase separation gel for long-term delivery of peptidesBiomaterials 45(2015)1-9
5.Jinjie Zhang, Jianbo Li, Yuan Ju, Yao Fu,Tao Gong*and Zhirong Zhang* Mechanism of enhanced oral absorption of morin by phospholipid complex based self-nanoemulsifying drug delivery system Molecular Pharmaceutics 2015,12（2）：504-513
6.Xinyi He, Nanxi Xiang, Jinjie Zhang, Yao Fu*,Tao Gong*Encapsulation of teniposide into albumin nanoparticles with greatly lowered toxicity and enhanced antitumor activity International Journal of Pharmaceutics 2015, 487（1-2）250–259
7.Quan Zhang,† Xuanmiao Zhang,† Tijia Chen, Xinyi Wang, Yao Fu, Yun Jin,* Xun Sun,Tao Gong*and Zhirong Zhang A safe and efficient hepatocyte-selective carrier system based on myristoylated preS1/21-47 domain of hepatitis B virus Nanoscale,2015,7, 9298 - 9310
8. Yanwei Teng, Min Bai, Ying sun, Qi Wang, Fan li, Jinfang Xing, lianfang Du,Tao Gong*, Yourong Duan*Enhanced delivery of Peal nanoparticles with ultrasound targeted microbubble destruction mediated siRNA transfection in human McF-7/s and McF-7/aDr cells in vitro International Journal of Nanomedicine 2015:10 5447–5457
9. Qing Lin, Yu Fu, Jia Li, Mengke Qu, Li Deng,Tao Gong*, Zhirong Zhang*A (polyvinyl caprolactam-polyvinyl acetate–polyethylene glycol graft copolymer)- dispersed sustained-release tablet for imperialine to simultaneously prolong the drug release and improve the oral bioavailabilityEuropean Journal ofPharmaceutical Sciences 79 (2015) 44–52
10.Huan Liu, Hua Lu, Longfei Liao, Xuanmiao Zhang,Tao Gong*, and Zhirong Zhang Lipid nanoparticles loaded with 7-ethyl-10-hydroxycamptothecin-phospholipid complex: in vitro and in vivo studies Drug Deliv, 2015; 22(6): 701–709
2014年
1. Xuanmiao Zhang, Quan Zhang, Qiang Peng, Jing Zhou, Longfei Liao, Xun Sun,
Ling Zhang*,Tao Gong*Hepatitis B virus preS1-derived lipopeptide functionalized liposomes for targeting of hepatic cells Biomaterials 35 (2014) 6130-6141
2. Wenqi Wu, Hui Chen , Fengying Shan, Jing Zhou, Xun Sun, Ling Zhang*,Tao Gong*A novel doxorubicin-loaded in situ forming gel based on high concentration phospholipid for intratumoral drug delivery Molecular Pharmaceutics 2014, 11 (10):3378–3385
3. Longfei Liao, Mengtian Zhang, Huan Liu, Xuanmiao Zhang, Zhaolu Xie,Zhirong Zhang,
Tao Gong* and Xun Sun* Subchronic toxicity and immunotoxicity of MeO-PEG-poly(D,L-lactic-co-glycolic
acid)-PEG-OMe triblock copolymer nanoparticles delivered intravenously into rats Nanotechnology
25 (2014) 245705
4. Xianghong Lian, Jianxia Dong, Jinjie Zhang, Yanwei Teng, Qing Lin, Yao Fu*,Tao Gong*Soluplus® based 9-nitrocamptothecin solid dispersion for peroral administration:Preparation, characterization, in vitro and in vivo evaluation International Journal of Pharmaceutics 2014,477(1-2):399-407
5. Man Li†, Zhen Liang†, Xun Sun,Tao Gong*, Zhirong Zhang* A polymeric prodrug of 5-fluorouracil-1-acetic acid using a multi-hydroxyl polyethylene glycol derivative as the drug carrier Plos One 2014, 9（11）：1-13
2013年
1. Ting Zhang, Yong Zheng, Qiang Peng, Xi Cao,Tao Gong*, Zhirong Zhang A novel submicron emulsion system loaded with vincristine–oleic acid ion-pair complex with improved anticancer effect: in vitro and in vivo studies International Journal of Nanomedicine 2013:8 1185–1196
2. Junlan Chuan, Yanzhen Li, Likai Yang, Xun Sun, Qiang Zhang,Tao Gong*, Zhirong Zhang Enhanced rifampicin delivery to alveolar macrophages by solid lipid nanoparticles J Nanopart Res (2013) 15:1634
3.Hui Zhao, Hua Lu,Tao Gong*, Zhirong ZhangNanoemulsion loaded with lycobetaine-oleic acid ionic complex: physicochemical characteristics, in vitro, in vivo evaluation and antitumor activity International Journal of Nanomedicine 2013:8 1959–1973
4. Likai Yang, Jing Luo, Sanjun Shi, Qiang Zhang, Xun Sun, Zhirong Zhang,Tao Gong*Development of a pulmonary peptide delivery system using porous nanoparticle-aggregate particles for systemic application International Journal of Pharmaceutics 451 (2013) 104–111
5. Mei Li, Yong Zheng, Fengying Shan, Jing Zhou,Tao Gong*, Zhirong Zhang
Development of ionic complex based nanostructured lipid carriers to improve pharmacokinetic profiles of breviscapine Acta Pharmacologica Sinica (2013) 34: 1108–1115
6. Ying Zhong, Liyu Chen, Yu Zhang, Wenhao Li, Xun Sun,Tao Gong*, Zhirong Zhang Vesicular phospholipid gels using low concentrations of phospholipids for the sustained release of thymopentin: pharmacokinetics and pharmacodynamics Die Pharmazie 68: 811–815 (2013)
7. Hualin FU, Zhirong ZHANG &Tao Gong*Influence of the Deacetylation Degree on the In Vivo Distribution of Chitosan in Mice Lat. Am. J. Pharm. 32 (8): 1178-83 (2013)
8. Jing Zhou, Xuanmiao Zhang, Mei Li, Wenqi Wu, Xun Sun, Ling Zhang*,Tao Gong*Novel lipid hybrid albumin nanoparticle greatly lowered toxicity of pirarubicin Molecular Pharmaceutics 2013, 10 (10)：3832–3841
2012年
1.Sanjun Shi, Zhirong Zhong, Jie Liu, Xun Sun,Tao Gong*and Zhirong Zhang Solid lipid nanoparticles loaded with anti-microRNA oligonucleotides (AMOs) for suppression of microRNA-21 functions in human lung cancer cells pharmaceutical research（2012）29：97-109
2. Xu Song, Yu Jiang, Chunjuan Ren, Xun Sun, Qiang Zhang,Tao Gong*, Zhirong Zhang* Nimodipine-loaded mixed micelles: formulation, compatibility, pharmacokinetics, and vascular irritability study International Journal of Nanomedicine 2012:7 3689–3699
3. Xing Liu, Wenhao Li, Zhen Liang, Xuan Zhang, YangmingGuo,Tao Gong*, and Zhirong Zhang Prednisolone-Glucose Derivative Conjugate: Synthesis, Biodistribution and Pharmacodynamics Evaluation Archiv der Pharmazie. Chemistry in Life Science（Arch. Pharm. Chem. Life Sci）. 2012,345（12）：925-33
4. Yangming Guo, Xing Liu, Xun Sun, Qiang Zhang,Tao Gong*, Zhirong Zhang* Mannosylated lipid nanoemulsions loaded with lycorine-oleic acid ionic complex for tumor site-specific delivery Theranostics, 2012; 2(11): 1104–1114.
2011年
1.Ruiling Duan, Jie Liu, Xun Sun,Tao Gong*，Zhirong Zhang*Mixed micelles loaded with silybin-polyene Phosphatidylcholine complex imprive drug solubilityActa Pharmacologica Sinica(2011) 32: 108–115
2.Xuanmiao Zhang1, Xun Sun1, Jilong Li1, Xiaoning Zhang2,Tao Gong*1,ZhirongZhang1 Lipid nanoemulsions loaded with doxorubicin-oleic acid ionic complex: characterization, in vitro and in vivo studies Die Pharmazie 2011, 66（7）: 496-505
3.Zhang Jinjie, Peng Qiang, Shi Sanjun, Zhang Qiang, Sun Xun,Gong Tao*, Zhang Zhirong* Preparation,Characterization, and in vivo evaluation of self-nanoemulsifying drug delivery systems (SNEDDSs) loaded with morin phospholipid complex International Journal of Nanomedicine 2011，6：3405–3414
2010年
1. Jinghua Ruana,b, Jie Liua,Tao Gonga*, Fumei Yangb, Xiaojiang Haob, Zhirong Zhanga* Preparation and evaluation of self-nanoemulsified drug delivery systems (SNEDDSs) of matrine based on drug-phospholipid complex technique International Journal of Pharmaceutics, 386 (2010) 282–290.
2. Qiang Peng, Zhi-Rong Zhang, Jiao Zuo, Xun Sun, Dong Zhao,Tao Gong*Mechanisms of Phospholipid Complex Loaded Nanoparticles Enhancing the Oral Bioavailability
Molecular Pharmaceutics, 2010，7（2）：565–575.
3. Yue Zhao, Jie Liu, Xun Sun, Zhi-Rong Zhang,Tao Gong*Sustained release of hydroxycamptothecin after subcutaneous administration using a novel phospholipid complex - DepoFoamTM technology Drug Development and Industrial Pharmacy, 2010, 36(7): 823-831
4. Wei Wei1, San-Jun Shi1, Jie Liu1, Xun Sun1, Ke Ren1, Dong Zhao1, Xiao-Ning Zhang2, Zhi-Rong Zhang1&Tao Gong1*Lipid nanoparticles loaded with 10-hydroxycamptothecin-phospholipid complex for liver targeting Journal of drug targeting, 2010, 18（7）：557-566
5. Xiaoyu Chen, Xun Sun, Ke Ren, Zhirong Zhang,Tao Gong*Enhanced aqueous solubility and bioavailability of capsaicin by the preparation of inclusion complex Arzneimittel Forschung Drug Research, 2010;60(9):571-574
6. Yan-Zhen Li & Xun Sun &Tao Gong*& Jie Liu & Jiao Zuo & Zhi-Rong Zhang*
Inhalable microparticles as a carrier for pulmonary delivery of thymopentin loaded solid lipid nanoparticles Pharmaceutical Research, (2010) 27:1977–1986
出版的主要著作：
1.张志荣主编。普通高等教育“十二五”国家级规划教材，全国高等学校药学类规划教材，《药剂学》(第二版)。高等教育出版社，2014，北京。
2.蒋新国主编。《脑靶向递药系统》 ，人民卫生出版社，2011，北京。
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4.张志荣主编。《靶向治疗分子基础与靶向药物设计》 ，科学出版社，2005,北京。
编辑：金沙威尼斯欢乐娱人城
